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In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors

BACKGROUND: The thymus is the primary site for T-cell development and induction of self-tolerance. Previous approaches towards manipulation of T-cell differentiation have used intrathymic injection of antigens, as proteins, cells or adenoviruses, leading to transient expression of the foreign protei...

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Autors principals: Marodon, Gilles, Klatzmann, David
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516029/
https://ncbi.nlm.nih.gov/pubmed/15318949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-5-18
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