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In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer

SCID patients have been successfully treated by administration of ex vivo gene-corrected stem cells. However, despite its proven efficacy, such treatment carries specific risks and difficulties. We hypothesized that some of these drawbacks may be overcome by in situ gene correction of T lymphoid pro...

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Detalhes bibliográficos
Main Authors: Adjali, Oumeya, Marodon, Gilles, Steinberg, Marcos, Mongellaz, Cédric, Thomas-Vaslin, Véronique, Jacquet, Chantal, Taylor, Naomi, Klatzmann, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180533/
https://ncbi.nlm.nih.gov/pubmed/16075064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23966
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