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In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer
SCID patients have been successfully treated by administration of ex vivo gene-corrected stem cells. However, despite its proven efficacy, such treatment carries specific risks and difficulties. We hypothesized that some of these drawbacks may be overcome by in situ gene correction of T lymphoid pro...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180533/ https://ncbi.nlm.nih.gov/pubmed/16075064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23966 |
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