Efficient Intrathymic Gene Transfer Following In Situ Administration of a rAAV Serotype 8 Vector in Mice and Nonhuman Primates

The thymus is the primary site of T-cell development and plays a key role in the induction of self-tolerance. We previously showed that the intrathymic (IT) injection of a transgene-expressing lentiviral vector (LV) in mice can result in the correction of a T cell–specific genetic defect. Neverthele...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Moreau, Aurélie, Vicente, Rita, Dubreil, Laurence, Adjali, Oumeya, Podevin, Guillaume, Jacquet, Chantal, Deschamps, Jack Yves, Klatzmann, David, Cherel, Yan, Taylor, Naomi, Moullier, Philippe, Zimmermann, Valérie S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835094/
https://ncbi.nlm.nih.gov/pubmed/19088703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.272
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados