Efficient Intrathymic Gene Transfer Following In Situ Administration of a rAAV Serotype 8 Vector in Mice and Nonhuman Primates

The thymus is the primary site of T-cell development and plays a key role in the induction of self-tolerance. We previously showed that the intrathymic (IT) injection of a transgene-expressing lentiviral vector (LV) in mice can result in the correction of a T cell–specific genetic defect. Neverthele...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Moreau, Aurélie, Vicente, Rita, Dubreil, Laurence, Adjali, Oumeya, Podevin, Guillaume, Jacquet, Chantal, Deschamps, Jack Yves, Klatzmann, David, Cherel, Yan, Taylor, Naomi, Moullier, Philippe, Zimmermann, Valérie S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835094/
https://ncbi.nlm.nih.gov/pubmed/19088703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.272
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares