Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle

In the absence of an immune response from the host, intramuscular (IM) injection of recombinant adeno-associated virus (rAAV) results in the permanent expression of the transgene from mouse to primate models. However, recent gene transfer studies into animal models and humans indicate that the risk...

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Detalhes bibliográficos
Main Authors: Toromanoff, Alice, Adjali, Oumeya, Larcher, Thibaut, Hill, Marcelo, Guigand, Lydie, Chenuaud, Pierre, Deschamps, Jack-Yves, Gauthier, Olivier, Blancho, Gilles, Vanhove, Bernard, Rolling, Fabienne, Chérel, Yan, Moullier, Philippe, Anegon, Ignacio, Le Guiner, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839209/
https://ncbi.nlm.nih.gov/pubmed/19888197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.251
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