Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle

In the absence of an immune response from the host, intramuscular (IM) injection of recombinant adeno-associated virus (rAAV) results in the permanent expression of the transgene from mouse to primate models. However, recent gene transfer studies into animal models and humans indicate that the risk...

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Dettagli Bibliografici
Autori principali: Toromanoff, Alice, Adjali, Oumeya, Larcher, Thibaut, Hill, Marcelo, Guigand, Lydie, Chenuaud, Pierre, Deschamps, Jack-Yves, Gauthier, Olivier, Blancho, Gilles, Vanhove, Bernard, Rolling, Fabienne, Chérel, Yan, Moullier, Philippe, Anegon, Ignacio, Le Guiner, Caroline
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839209/
https://ncbi.nlm.nih.gov/pubmed/19888197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.251
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