Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle

In the absence of an immune response from the host, intramuscular (IM) injection of recombinant adeno-associated virus (rAAV) results in the permanent expression of the transgene from mouse to primate models. However, recent gene transfer studies into animal models and humans indicate that the risk...

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書誌詳細
主要な著者: Toromanoff, Alice, Adjali, Oumeya, Larcher, Thibaut, Hill, Marcelo, Guigand, Lydie, Chenuaud, Pierre, Deschamps, Jack-Yves, Gauthier, Olivier, Blancho, Gilles, Vanhove, Bernard, Rolling, Fabienne, Chérel, Yan, Moullier, Philippe, Anegon, Ignacio, Le Guiner, Caroline
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2009
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839209/
https://ncbi.nlm.nih.gov/pubmed/19888197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.251
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