Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle

In the absence of an immune response from the host, intramuscular (IM) injection of recombinant adeno-associated virus (rAAV) results in the permanent expression of the transgene from mouse to primate models. However, recent gene transfer studies into animal models and humans indicate that the risk...

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Bibliografski detalji
Glavni autori: Toromanoff, Alice, Adjali, Oumeya, Larcher, Thibaut, Hill, Marcelo, Guigand, Lydie, Chenuaud, Pierre, Deschamps, Jack-Yves, Gauthier, Olivier, Blancho, Gilles, Vanhove, Bernard, Rolling, Fabienne, Chérel, Yan, Moullier, Philippe, Anegon, Ignacio, Le Guiner, Caroline
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2009
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839209/
https://ncbi.nlm.nih.gov/pubmed/19888197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.251
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