Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer

Preventing untoward immune responses against a specific antigen is a major challenge in different clinical settings such as gene therapy, transplantation, or autoimmunity. Following intramuscular delivery of recombinant adeno-associated virus (rAAV)-derived vectors, transgene rejection can be a road...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Moreau, Aurélie, Vandamme, Céline, Segovia, Mercedes, Devaux, Marie, Guilbaud, Mickaël, Tilly, Gaëlle, Jaulin, Nicolas, Le Duff, Johanne, Cherel, Yan, Deschamps, Jack-Yves, Anegon, Ignacio, Moullier, Philippe, Cuturi, Maria Cristina, Adjali, Oumeya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420248/
https://ncbi.nlm.nih.gov/pubmed/26015970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.28
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