Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency

Patients with severe combined immunodeficiency (SCID) present with opportunistic infections that are almost universally fatal in infancy. The mainstay treatment for these patients is allogeneic hematopoietic stem cell (HSC) transplantation, but sustained polyclonal T cell reconstitution is too often...

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Autors principals: Adjali, Oumeya, Vicente, Rita R., Ferrand, Christophe, Jacquet, Chantal, Mongellaz, Cédric, Tiberghien, Pierre, Chebli, Karim, Zimmermann, Valérie S., Taylor, Naomi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224628/
https://ncbi.nlm.nih.gov/pubmed/16174749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504268102
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