Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency

Patients with severe combined immunodeficiency (SCID) present with opportunistic infections that are almost universally fatal in infancy. The mainstay treatment for these patients is allogeneic hematopoietic stem cell (HSC) transplantation, but sustained polyclonal T cell reconstitution is too often...

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Detalhes bibliográficos
Main Authors: Adjali, Oumeya, Vicente, Rita R., Ferrand, Christophe, Jacquet, Chantal, Mongellaz, Cédric, Tiberghien, Pierre, Chebli, Karim, Zimmermann, Valérie S., Taylor, Naomi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224628/
https://ncbi.nlm.nih.gov/pubmed/16174749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504268102
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