Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency

Patients with severe combined immunodeficiency (SCID) present with opportunistic infections that are almost universally fatal in infancy. The mainstay treatment for these patients is allogeneic hematopoietic stem cell (HSC) transplantation, but sustained polyclonal T cell reconstitution is too often...

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Hlavní autoři: Adjali, Oumeya, Vicente, Rita R., Ferrand, Christophe, Jacquet, Chantal, Mongellaz, Cédric, Tiberghien, Pierre, Chebli, Karim, Zimmermann, Valérie S., Taylor, Naomi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224628/
https://ncbi.nlm.nih.gov/pubmed/16174749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504268102
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