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Simplified production and concentration of lentiviral vectors to achieve high transduction in primary human T cells

BACKGROUND: Lentiviral vectors have emerged as efficient vehicles for transgene delivery in both dividing and non-dividing cells. A number of different modifications in vector design have increased biosafety and transgene expression. However, despite these advances, the transduction of primary human...

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Autori principali: Cribbs, Adam P, Kennedy, Alan, Gregory, Bernard, Brennan, Fionula M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830501/
https://ncbi.nlm.nih.gov/pubmed/24215295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-13-98
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