Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic β cells through activation of phosphatidylinositol 4-kinase β

Cytosolic free Ca(2+) plays an important role in the molecular mechanisms leading to regulated insulin secretion by the pancreatic β cell. A number of Ca(2+)-binding proteins have been implicated in this process. Here, we define the role of the Ca(2+)-binding protein neuronal Ca(2+) sensor-1 (NCS-1)...

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Detalhes bibliográficos
Main Authors: Gromada, Jesper, Bark, Christina, Smidt, Kamille, Efanov, Alexander M., Janson, Juliette, Mandic, Slavena A., Webb, Dominic-Luc, Zhang, Wei, Meister, Björn, Jeromin, Andreas, Berggren, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177407/
https://ncbi.nlm.nih.gov/pubmed/16014415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504487102
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