Munc18-1 and Munc18-2 Proteins Modulate β-Cell Ca(2+) Sensitivity and Kinetics of Insulin Exocytosis Differently

Fast neurotransmission and slower hormone release share the same core fusion machinery consisting of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins. In evoked neurotransmission, interactions between SNAREs and the Munc18-1 protein, a member of the Sec1/Munc18...

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Main Authors: Mandic, Slavena A., Skelin, Masa, Johansson, Jenny U., Rupnik, Marjan S., Berggren, Per-Olof, Bark, Christina
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151048/
https://ncbi.nlm.nih.gov/pubmed/21690086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.235366
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