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Inhibition of IFN-α signaling by a PKC- and protein tyrosine phosphatase SHP-2-dependent pathway

Cytokine signaling by the Jak–STAT pathway is subject to complex negative regulation that limits the amplitude and duration of signal transduction. Inhibition of signaling also mediates negative crosstalk, whereby factors with opposing biological activities crossinhibit each other's function. H...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Du, Zhimei, Shen, Yuhong, Yang, Wentian, Mecklenbrauker, Ingrid, Neel, Benjamin G., Ivashkiv, Lionel B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177356/
https://ncbi.nlm.nih.gov/pubmed/16000408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408854102
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