載入...

Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase

Human 8-oxoguanine-DNA glycosylase (hOgg1) excises 8-oxo-7,8-dihydroguanine (8-oxoG) from damaged DNA. We report a pre-steady-state kinetic analysis of hOgg1 mechanism using stopped-flow and enzyme fluorescence monitoring. The kinetic scheme for hOgg1 processing an 8-oxoG:C-containing substrate was...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Kuznetsov, Nikita A., Koval, Vladimir V., Zharkov, Dmitry O., Nevinsky, Georgy A., Douglas, Kenneth T., Fedorova, Olga S.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2005
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176011/
https://ncbi.nlm.nih.gov/pubmed/16024742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki694
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!