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Uracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition
Uracil appears in DNA as a result of cytosine deamination and by incorporation from the dUTP pool. As potentially mutagenic and deleterious for cell regulation, uracil must be removed from DNA. The major pathway of its repair is initiated by uracil-DNA glycosylases (UNG), ubiquitously found enzymes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000906/ https://ncbi.nlm.nih.gov/pubmed/19909758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.10.017 |
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