Loading...
Effect of HIV integrase inhibitors on the RAG1/2 recombinase
Assembly of functional Ig and T cell receptor genes by V(D)J recombination depends on site-specific cleavage of chromosomal DNA by the RAG1/2 recombinase. As RAG1/2 action has mechanistic similarities to DNA transposases and integrases such as HIV-1 integrase, we sought to determine how integrase in...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
2002
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117527/ https://ncbi.nlm.nih.gov/pubmed/11756686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012610699 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|