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Replication-associated strand asymmetries in mammalian genomes: Toward detection of replication origins
In the course of evolution, mutations do not affect both strands of genomic DNA equally. This imbalance mainly results from asymmetric DNA mutation and repair processes associated with replication and transcription. In prokaryotes, prevalence of G over C and T over A is frequently observed in the le...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174978/ https://ncbi.nlm.nih.gov/pubmed/15985556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500577102 |
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