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Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction

Mitochondrial DNA (mtDNA) contains high levels of oxidative damage relative to nuclear DNA. A full, functional DNA base excision repair (BER) pathway is present in mitochondria, to repair oxidative DNA lesions. However, little is known about the organization of this pathway within mitochondria. Here...

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Hlavní autoři: Stuart, J. A., Mayard, S., Hashiguchi, K., Souza-Pinto, N. C., Bohr, V. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174906/
https://ncbi.nlm.nih.gov/pubmed/16006620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki683
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