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Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction
Mitochondrial DNA (mtDNA) contains high levels of oxidative damage relative to nuclear DNA. A full, functional DNA base excision repair (BER) pathway is present in mitochondria, to repair oxidative DNA lesions. However, little is known about the organization of this pathway within mitochondria. Here...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174906/ https://ncbi.nlm.nih.gov/pubmed/16006620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki683 |
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