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Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1

In higher eukaryotes the biogenesis of spliceosomal UsnRNPs involves a nucleocytoplasmic shuttling cycle. After the m(7)G-cap-dependent export of the snRNAs U1, U2, U4 and U5 to the cytoplasm, each of these snRNAs associates with seven Sm proteins. Subsequently, the m(7)G-cap is hypermethylated to t...

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Detalhes bibliográficos
Main Authors: Strasser, Anja, Dickmanns, Achim, Lührmann, Reinhard, Ficner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173142/
https://ncbi.nlm.nih.gov/pubmed/15920472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600701
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