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Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1
In higher eukaryotes the biogenesis of spliceosomal UsnRNPs involves a nucleocytoplasmic shuttling cycle. After the m(7)G-cap-dependent export of the snRNAs U1, U2, U4 and U5 to the cytoplasm, each of these snRNAs associates with seven Sm proteins. Subsequently, the m(7)G-cap is hypermethylated to t...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1173142/ https://ncbi.nlm.nih.gov/pubmed/15920472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600701 |
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