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Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs

Although spliceosomal Sm proteins can assemble spontaneously onto UsnRNA in vitro, this process requires assisting factors in vivo. SMN, the protein involved in spinal muscular atrophy, is part of a complex that contains the Sm proteins and serves as a critical factor for this reaction. Here, we hav...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Meister, Gunter, Fischer, Utz
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC131082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf585
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