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Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs

Although spliceosomal Sm proteins can assemble spontaneously onto UsnRNA in vitro, this process requires assisting factors in vivo. SMN, the protein involved in spinal muscular atrophy, is part of a complex that contains the Sm proteins and serves as a critical factor for this reaction. Here, we hav...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Meister, Gunter, Fischer, Utz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC131082/
https://ncbi.nlm.nih.gov/pubmed/12411503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf585
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