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Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis

Spliceosomal small nuclear ribonucleoproteins (snRNPs) are enriched in the Cajal body (CB). Guide RNAs, known as small Cajal body-specific RNAs (scaRNAs), direct modification of the small nuclear RNA (snRNA) component of the snRNP. The protein WRAP53 binds a sequence motif (the CAB box) found in man...

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Principais autores: Isioma I. Enwerem, Venkatramreddy Velma, Hanna J. Broome, Marija Kuna, Rowshan A. Begum, Michael D. Hebert
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2014-07-01
Serier:Biology Open
Fag:
Cajal body
Coilin
snRNA
Online adgang:http://bio.biologists.org/content/3/4/240
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