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Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs

Although spliceosomal Sm proteins can assemble spontaneously onto UsnRNA in vitro, this process requires assisting factors in vivo. SMN, the protein involved in spinal muscular atrophy, is part of a complex that contains the Sm proteins and serves as a critical factor for this reaction. Here, we hav...

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Bibliographic Details
Published in:EMBO J
Main Authors: Meister, Gunter, Fischer, Utz
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC131082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf585
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