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Evolution of an RNP assembly system: A minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster

In vertebrates, assembly of spliceosomal uridine-rich small nuclear ribonucleoproteins (UsnRNPs) is mediated by the SMN complex, a macromolecular entity composed of the proteins SMN and Gemins 2–8. Here we have studied the evolution of this machinery using complete genome assemblies of multiple mode...

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Detalhes bibliográficos
Main Authors: Kroiss, Matthias, Schultz, Jörg, Wiesner, Julia, Chari, Ashwin, Sickmann, Albert, Fischer, Utz
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481332/
https://ncbi.nlm.nih.gov/pubmed/18621711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802287105
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