Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation

Specialized assembly factors facilitate the formation of many macromolecular complexes in vivo. The formation of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requires assembly factors united in protein arginine methyltransferase 5 (PRMT5) and survival...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Prusty, Archana Bairavasundaram, Meduri, Rajyalakshmi, Prusty, Bhupesh Kumar, Vanselow, Jens, Schlosser, Andreas, Fischer, Utz
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551706/
https://ncbi.nlm.nih.gov/pubmed/28637748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611108
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