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Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation
Specialized assembly factors facilitate the formation of many macromolecular complexes in vivo. The formation of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requires assembly factors united in protein arginine methyltransferase 5 (PRMT5) and survival...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551706/ https://ncbi.nlm.nih.gov/pubmed/28637748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611108 |
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