Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

Lignende værker

• Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters
  af: Loughery, Jayne, et al.
  Udgivet: (2014)
• Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover.
  af: Dumaz, N, et al.
  Udgivet: (2001)
• Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.
  af: Lees-Miller, S P, et al.
  Udgivet: (1992)
• HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
  af: Linares, Laëtitia K., et al.
  Udgivet: (2003)
• Mutation of the serine 312 phosphorylation site does not alter the ability of mouse p53 to inhibit simian virus 40 DNA replication in vivo.
  af: Meek, D W, et al.
  Udgivet: (1990)