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A developmental switch in H4 acetylation upstream of Xist plays a role in X chromosome inactivation.
We have investigated the role of histone acetylation in X chromosome inactivation, focusing on its possible involvement in the regulation of Xist, an essential gene expressed only from the inactive X (Xi). We have identified a region of H4 hyperacetylation extending up to 120 kb upstream from the Xi...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171370/ https://ncbi.nlm.nih.gov/pubmed/10329635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.10.2897 |
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