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Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?

C2-domains are widespread protein modules with diverse Ca2+-regulatory functions. Although multiple Ca2+ ions are known to bind at the tip of several C2-domains, the exact number of Ca2+-binding sites and their functional relevance are unknown. The first C2-domain of synaptotagmin I is believed to p...

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Autors principals: Ubach, J, Zhang, X, Shao, X, Südhof, T C, Rizo, J
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170727/
https://ncbi.nlm.nih.gov/pubmed/9670009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.3921
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