Ku80 is required for immunoglobulin isotype switching.

Isotype switching is the DNA recombination mechanism by which antibody genes diversify immunoglobulin effector functions. In contrast to V(D)J recombination, which is mediated by RAG1, RAG2 and DNA double-stranded break (DSB) repair proteins, little is known about the mechanism of switching. We have...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Casellas, R, Nussenzweig, A, Wuerffel, R, Pelanda, R, Reichlin, A, Suh, H, Qin, X F, Besmer, E, Kenter, A, Rajewsky, K, Nussenzweig, M C
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170583/
https://ncbi.nlm.nih.gov/pubmed/9545251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.8.2404
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados