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Origin of immunoglobulin isotype switching
BACKGROUND: From humans to frogs, immunoglobulin class switching introduces different effector functions to antibodies through an intrachromsomal DNA recombination process at the heavy chain locus. Although there are two conventional antibody classes (IgM, IgW) in sharks, their heavy chains are enco...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360817/ https://ncbi.nlm.nih.gov/pubmed/22542103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.03.060 |
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