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Shark IgW C region diversification through RNA processing and isotype switching

Sharks and skates represent the earliest vertebrates with an adaptive immune system based on lymphocyte antigen receptors generated by V(D)J recombination. Shark B cells express two classical immunoglobulins (Ig), IgM and IgW, encoded by an early, alternative gene organization consisting of numerous...

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Autors principals: Zhang, Cecilia, Du Pasquier, Louis, Hsu, Ellen
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839419/
https://ncbi.nlm.nih.gov/pubmed/23935192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301257
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