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Shark IgW C region diversification through RNA processing and isotype switching
Sharks and skates represent the earliest vertebrates with an adaptive immune system based on lymphocyte antigen receptors generated by V(D)J recombination. Shark B cells express two classical immunoglobulins (Ig), IgM and IgW, encoded by an early, alternative gene organization consisting of numerous...
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Autors principals: | , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2013
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839419/ https://ncbi.nlm.nih.gov/pubmed/23935192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301257 |
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