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The Evolution of Multiple Isotypic IgM Heavy Chain Genes in the Shark

The IgM H chain gene organization of cartilaginous fishes consists of 15–200 miniloci, each with a few gene segments (V(H)-D1-D2-J(H)) and one C gene. This is a gene arrangement ancestral to the complex IgH locus that exists in all other vertebrate classes. To understand the molecular evolution of t...

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Detalhes bibliográficos
Main Authors: Lee, Victor, Huang, Jing Li, Lui, Ming Fai, Malecek, Karolina, Ohta, Yuko, Mooers, Arne, Hsu, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590587/
https://ncbi.nlm.nih.gov/pubmed/18490746
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