Immunoglobulin Heavy Chain Exclusion in the Shark

The adaptive immune system depends on specific antigen receptors, immunoglobulins (Ig) in B lymphocytes and T cell receptors (TCR) in T lymphocytes. Adaptive responses to immune challenge are based on the expression of a single species of antigen receptor per cell; and in B cells, this is mediated i...

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Bibliographic Details
Main Authors: Malecek, Karolina, Lee, Victor, Feng, Wendy, Huang, Jing Li, Flajnik, Martin F, Ohta, Yuko, Hsu, Ellen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435157/
https://ncbi.nlm.nih.gov/pubmed/18578572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060157
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