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Evidence for Class-Specific Factors in Immunoglobulin Isotype Switching

Immunoglobulin class switch recombination (SR) occurs by a B cell–specific, intrachromosomal deletional process between switch regions. We have developed a plasmid-based transient transfection assay for SR to test for the presence of transacting switch activities. The plasmids are novel in that they...

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Detalhes bibliográficos
Main Authors: Shanmugam, Ananth, Shi, Meng-Jiao, Yauch, Lauren, Stavnezer, Janet, Kenter, Amy L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193137/
https://ncbi.nlm.nih.gov/pubmed/10770803
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