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Impaired Rescue of Chain-Terminated DNA Synthesis Associated with the L74V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase

The L74V and M184V mutations in the reverse transcriptase (RT) gene of human immunodeficiency virus type 1 (HIV-1) are frequently associated with resistance to the nucleoside reverse transcriptase inhibitors abacavir, didanosine, and lamivudine. Yet viruses containing any of these mutations often di...

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Main Authors: Frankel, Fernando A., Marchand, Bruno, Turner, Dan, Götte, Matthias, Wainberg, Mark A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168713/
https://ncbi.nlm.nih.gov/pubmed/15980333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2657-2664.2005
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