Effects of the Translocation Status of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on the Efficiency of Excision of Tenofovir

The ATP-dependent phosphorolytic excision of nucleoside analogue reverse transcriptase inhibitors can diminish their inhibitory effects on human immunodeficiency virus replication. Previous studies have shown that excision can occur only when the reverse transcriptase complex exists in its pretransl...

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Detalhes bibliográficos
Main Authors: Marchand, Bruno, White, Kirsten L., Ly, John K., Margot, Nicolas A., Wang, Ruth, McDermott, Martin, Miller, Michael D., Götte, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932533/
https://ncbi.nlm.nih.gov/pubmed/17517852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00314-07
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