Loading...

Phosphorylation of Simian Virus 40 T Antigen on Thr 124 Selectively Promotes Double-Hexamer Formation on Subfragments of the Viral Core Origin

Cell cycle-dependent phosphorylation of simian virus 40 (SV40) large tumor antigen (T-ag) on threonine 124 is essential for the initiation of viral DNA replication. A T-ag molecule containing a Thr→Ala substitution at this position (T124A) was previously shown to bind to the SV40 core origin but to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Barbaro, Brett A., Sreekumar, K. R., Winters, Danielle R., Prack, Andrea E., Bullock, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC116373/
https://ncbi.nlm.nih.gov/pubmed/10954562
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!