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HIF-1α expression regulates the bactericidal capacity of phagocytes
Hypoxia is a characteristic feature of the tissue microenvironment during bacterial infection. Here we report on our use of conditional gene targeting to examine the contribution of hypoxia-inducible factor 1, α subunit (HIF-1α) to myeloid cell innate immune function. HIF-1α was induced by bacterial...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1159132/ https://ncbi.nlm.nih.gov/pubmed/16007254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23865 |
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