Effect on Polyomavirus T-Antigen Function of Mutations in a Conserved Leucine-Rich Segment of the DnaJ Domain

The N-terminal part of the mouse polyomavirus T antigens contains a highly conserved segment (-LLELLKL-), including amino acid residues 13 to 19. The sequence motif is predicted to form alpha helix I in the DnaJ domain of the T antigens. Four mutants with conservative substitutions of amino acid res...

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Autores principales: Li, Hongyun, Söderbärg, Karin, Houshmand, Hamid, You, Zhi-Yong, Magnusson, Göran
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114809/
https://ncbi.nlm.nih.gov/pubmed/11160729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2253-2261.2001
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