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Effect on Polyomavirus T-Antigen Function of Mutations in a Conserved Leucine-Rich Segment of the DnaJ Domain

The N-terminal part of the mouse polyomavirus T antigens contains a highly conserved segment (-LLELLKL-), including amino acid residues 13 to 19. The sequence motif is predicted to form alpha helix I in the DnaJ domain of the T antigens. Four mutants with conservative substitutions of amino acid res...

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Publicado no:J Virol
Principais autores: Li, Hongyun, Söderbärg, Karin, Houshmand, Hamid, You, Zhi-Yong, Magnusson, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2253-2261.2001
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