The J Domain of Simian Virus 40 Large T Antigen Is Required To Functionally Inactivate RB Family Proteins

Transformation by simian virus 40 large T antigen (TAg) is dependent on the inactivation of cellular tumor suppressors. Transformation minimally requires the following three domains: (i) a C-terminal domain that mediates binding to p53; (ii) the LXCXE domain (residues 103 to 107), necessary for bind...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Zalvide, Juan, Stubdal, Hilde, DeCaprio, James A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1408
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