The J Domain of Simian Virus 40 Large T Antigen Is Required To Functionally Inactivate RB Family Proteins
Transformation by simian virus 40 large T antigen (TAg) is dependent on the inactivation of cellular tumor suppressors. Transformation minimally requires the following three domains: (i) a C-terminal domain that mediates binding to p53; (ii) the LXCXE domain (residues 103 to 107), necessary for bind...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1408 |
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