Macrophage Tropism of Human Immunodeficiency Virus Type 1 Isolates from Brain and Lymphoid Tissues Predicts Neurotropism Independent of Coreceptor Specificity

The viral determinants that underlie human immunodeficiency virus type 1 (HIV-1) neurotropism are unknown, due in part to limited studies on viruses isolated from brain. Previous studies suggest that brain-derived viruses are macrophage tropic (M-tropic) and principally use CCR5 for virus entry. To...

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Bibliographische Detailangaben
Hauptverfasser: Gorry, Paul R., Bristol, Greg, Zack, Jerome A., Ritola, Kimberly, Swanstrom, Ronald, Birch, Chris J., Bell, Jeanne E., Bannert, Norbert, Crawford, Keith, Wang, Hui, Schols, Dominique, De Clercq, Erik, Kunstman, Kevin, Wolinsky, Steven M., Gabuzda, Dana
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114582/
https://ncbi.nlm.nih.gov/pubmed/11581376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10073-10089.2001
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