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Macrophage Tropism of Human Immunodeficiency Virus Type 1 Isolates from Brain and Lymphoid Tissues Predicts Neurotropism Independent of Coreceptor Specificity

The viral determinants that underlie human immunodeficiency virus type 1 (HIV-1) neurotropism are unknown, due in part to limited studies on viruses isolated from brain. Previous studies suggest that brain-derived viruses are macrophage tropic (M-tropic) and principally use CCR5 for virus entry. To...

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Detalhes bibliográficos
Main Authors: Gorry, Paul R., Bristol, Greg, Zack, Jerome A., Ritola, Kimberly, Swanstrom, Ronald, Birch, Chris J., Bell, Jeanne E., Bannert, Norbert, Crawford, Keith, Wang, Hui, Schols, Dominique, De Clercq, Erik, Kunstman, Kevin, Wolinsky, Steven M., Gabuzda, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114582/
https://ncbi.nlm.nih.gov/pubmed/11581376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10073-10089.2001
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