Lanean...
Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5
Macrophages express low levels of the CD4 receptor compared to T-cells. Macrophagetropic HIV strains replicating in brain of untreated patients with HIV-associated dementia (HAD) express Envs that adapted to overcome this restriction through mechanisms that are poorly understood. Here, bioinformatic...
Gorde:
| Argitaratua izan da: | Virology |
|---|---|
| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437837/ https://ncbi.nlm.nih.gov/pubmed/25797607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.01.032 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|