Bioinformatic Prediction Programs Underestimate the Frequency of CXCR4 Usage by R5X4 HIV Type 1 in Brain and Other Tissues

Human immunodeficiency virus (HIV-1) variants in brain primarily use CCR5 for entry into macrophages and microglia, but dual-tropic (R5X4) HIV-1 has been detected in brain and cerebral spinal fluid (CSF) of some patients with HIV-associated dementia (HAD). Here, we sequenced the gp120 coding region...

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Main Authors: Mefford, Megan E., Gorry, Paul R., Kunstman, Kevin, Wolinsky, Steven M., Gabuzda, Dana
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2008
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Sequence Notes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801411/
https://ncbi.nlm.nih.gov/pubmed/18788913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2008.0009
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