Efficient Lymphoreticular Prion Propagation Requires PrP(c) in Stromal and Hematopoietic Cells

In most prion diseases, infectivity accumulates in lymphoreticular organs early after infection. Defects in hematopoietic compartments, such as impaired B-cell maturation, or in stromal compartments, such as abrogation of follicular dendritic cells, can delay or prevent lymphoreticular prion coloniz...

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Detalles Bibliográficos
Main Authors: Kaeser, Pascal S., Klein, Michael A., Schwarz, Petra, Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114438/
https://ncbi.nlm.nih.gov/pubmed/11435590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7097-7106.2001
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