Efficient Lymphoreticular Prion Propagation Requires PrP(c) in Stromal and Hematopoietic Cells

In most prion diseases, infectivity accumulates in lymphoreticular organs early after infection. Defects in hematopoietic compartments, such as impaired B-cell maturation, or in stromal compartments, such as abrogation of follicular dendritic cells, can delay or prevent lymphoreticular prion coloniz...

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Pubblicato in:	J Virol
Autori principali:	Kaeser, Pascal S., Klein, Michael A., Schwarz, Petra, Aguzzi, Adriano
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114438/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11435590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.15.7097-7106.2001
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