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Efficient Lymphoreticular Prion Propagation Requires PrP(c) in Stromal and Hematopoietic Cells
In most prion diseases, infectivity accumulates in lymphoreticular organs early after infection. Defects in hematopoietic compartments, such as impaired B-cell maturation, or in stromal compartments, such as abrogation of follicular dendritic cells, can delay or prevent lymphoreticular prion coloniz...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114438/ https://ncbi.nlm.nih.gov/pubmed/11435590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7097-7106.2001 |
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