Axonal Damage Is T Cell Mediated and Occurs Concomitantly with Demyelination in Mice Infected with a Neurotropic Coronavirus

Mice infected with mouse hepatitis virus (MHV) strain JHM develop primary demyelination. Herein we show that axonal damage occurred in areas of demyelination and also in adjacent areas devoid of myelin damage. Immunodeficient MHV-infected RAG1−/− mice (mice defective in recombinase activating gene 1...

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書誌詳細

出版年:	J Virol
主要な著者:	Dandekar, Ajai A., Wu, Gregory F., Pewe, Lecia, Perlman, Stanley
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2001
主題:	Pathogenesis and Immunity
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114327/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6115-6120.2001
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