Trypsin Cleavage Stabilizes the Rotavirus VP4 Spike

Trypsin enhances rotavirus infectivity by an unknown mechanism. To examine the structural basis of trypsin-enhanced infectivity in rotaviruses, SA11 4F triple-layered particles (TLPs) grown in the absence (nontrypsinized rotavirus [NTR]) or presence (trypsinized rotavirus [TR]) of trypsin were chara...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Crawford, Sue E., Mukherjee, Sharmila K., Estes, Mary K., Lawton, Jeffery A., Shaw, Andrea L., Ramig, Robert F., Prasad, B. V. Venkataram
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Structure and Assembly
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6052-6061.2001
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