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Identification of Rotavirus VP6 Residues Located at the Interface with VP2 That Are Essential for Capsid Assembly and Transcriptase Activity

Rotavirus has a complex triple-layered icosahedral capsid. The external layer consists of VP7 and VP4, the intermediate layer consists of VP6 trimers, and the internal layer consists of VP2. Double-layered particles (DLP) derived from the virus by solubilization of VP4 and VP7 are transcriptionally...

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Détails bibliographiques
Auteurs principaux: Charpilienne, Annie, Lepault, Jean, Rey, Felix, Cohen, Jean
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC136406/
https://ncbi.nlm.nih.gov/pubmed/12097594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.15.7822-7831.2002
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