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Identification of Rotavirus VP6 Residues Located at the Interface with VP2 That Are Essential for Capsid Assembly and Transcriptase Activity

Rotavirus has a complex triple-layered icosahedral capsid. The external layer consists of VP7 and VP4, the intermediate layer consists of VP6 trimers, and the internal layer consists of VP2. Double-layered particles (DLP) derived from the virus by solubilization of VP4 and VP7 are transcriptionally...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Charpilienne, Annie, Lepault, Jean, Rey, Felix, Cohen, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12097594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.15.7822-7831.2002
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