Trypsin Cleavage Stabilizes the Rotavirus VP4 Spike

Trypsin enhances rotavirus infectivity by an unknown mechanism. To examine the structural basis of trypsin-enhanced infectivity in rotaviruses, SA11 4F triple-layered particles (TLPs) grown in the absence (nontrypsinized rotavirus [NTR]) or presence (trypsinized rotavirus [TR]) of trypsin were chara...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Crawford, Sue E., Mukherjee, Sharmila K., Estes, Mary K., Lawton, Jeffery A., Shaw, Andrea L., Ramig, Robert F., Prasad, B. V. Venkataram
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Structure and Assembly
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6052-6061.2001
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